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| interleukin 9 ： ウィキペディア英語版 |
interleukin 9
Interleukin 9, also known as IL-9, is a cytokine (cell signalling molecule) belonging to the group of interleukins.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3578 )〕
== Function ==
The protein encoded by this gene is a cytokine produced by T-cells and specifically by CD4+ helper cells that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin-9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.〔
Interleukin-9 has also shown to inhibit melanoma growth in mice.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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